49ers receivers Mike Evans and Deebo Samuel Sr., and defensive end Nick Bosa are among a half dozen players who have been ruled out for Sunday's game against the Falcons.
49ers general manager John Lynch said the team has begun negotiations with quarterback Brock Purdy about a long-term contract.
The dynamic receiver/running back wants to move on after another struggling season.
The 49ers have granted Deebo Samuel Sr. and his agent, Tory Dandy, permission to seek a trade.
The 49ers said Wednesday they plan to release defensive tackle Javon Hargrave with a post-June 1 designation, but that wide receiver Deebo Samuel Sr. is not going anywhere.
San Francisco wide receiver Deebo Samuel on Tuesday stood by the sentiment he expressed in a since-deleted social media post in which he attributed his downturn in production to a lack of opportunities.
